Transcriptional profiling of gastrocnemius from rats exposed to partial weight bearing treatment to mimic Martian gravity
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https://osdr.nasa.gov/bio/repo/data/studies/OSD-418
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资源简介：
To understand the effects of Martian gravity (40% Earth) on mammals, 14-week-old female Wistar rats were exposed to quadrupedal partial weight bearing (PWB) treatment by suspending the entire animal in a quadrupedal unloading apparatus. Treatments were based on mimicking the gravity experienced on Earth (100% weight bearing, PWB100) and Mars (40% weight bearing, PWB40). After a 14-day treatment at PWB100 or PWB40, rats were euthanized and gastrocnemius muscles dissected and preserved in RNALater. Subsequently, RNA was extracted, and libraries generated using a 3’ Tag-seq approach and sequenced at a depth of 40 M clusters (SE 93 bp). This dataset features data from PWB40 (n of 4) and PWB100 (n of 4) animals.
提供机构：
NASA GeneLab
创建时间：
2021-09-03
