Genome-wide analysis of gene expression changes in mouse keratinocytes induced by treatment with DAPT

ChEBI2014-05-25 更新2026-07-21 收录

Notch信号通路药理研究

角质形成细胞转录组学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35090 数据链接链接失效反馈

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Genome-wide analysis of gene expression changes in mouse keratinocytes induced by treatment with DAPT

创建时间：

2014-05-25

IL-1 treatment of human epidermal keratinocytes. Homo sapiens

皮肤炎症机制

角质形成细胞转录组学

Interleukin-1 is a proinflammatory and immunomodulatory cytokine that plays a crucial role in inflammatory diseases of the skin, including bacterial infections, bullous diseases, UV damage and especia

NIAID Data Ecosystem100

âTranscriptomics Analysis Of SOCS3-deficient keratinocytes: Reveled Insights Into Progression of Chronic Skin Disease

疾病分子机制

角质形成细胞转录组学

We analyzed time series transcriptomics data of SOCS3 conditional knockout keratinocytes mice at 2, 8 and 10 week by using RNA-Sequencing technology to gain a basic understanding on the role of SOCS3

NIAID Data Ecosystem80

Expression data from keratinocytes treated either with IL-22 or combination of tofacitinib (JAK1/3 inhibitor) and IL-22 at 6 hours. Expression data from keratinocytes treated either with IL-22 or combination of tofacitinib (JAK1/3 inhibitor) and IL-22 at 6 hours

银屑病药物机制

角质形成细胞转录组学

JAK inhibitors like tofacitinib were thought to act primarily on T cells. However, our data and recent research suggest that JAK receptors are also present on keratinocytes. Here, we show effect of to

NIAID Data Ecosystem30

Next Generation Sequencing Facilitates Quantitative Analysis of Primary Keratinocytes and OSM-treated Primary Keratinocytes Transcriptomes. Next Generation Sequencing Facilitates Quantitative Analysis of Primary Keratinocytes and OSM-treated Primary Keratinocytes Transcriptomes

角质形成细胞转录组学

刺激响应

Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare transcriptome profiling (RNA-seq) between Primary Kerat

NIAID Data Ecosystem90

Different response of WT and Ts keratinocyte to TPA treatment

皮肤细胞药物反应

角质形成细胞转录组学

Ts keratinocyte has increased proliferation compare to WT keratinocyte upon TPA treatment. This result showed the different transcription regulation in Ts and WT keratinocyte upon TPA treatment. Total

NIAID Data Ecosystem40

Genome-wide analysis of gene expression changes in mouse keratinocytes induced by treatment with DAPT

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