X-ray structure of D25N chemical analogue of HIV-1 protease complexed with ketomethylene isostere inhibitor
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X-ray structure of D25N chemical analogue of HIV-1 protease complexed with ketomethylene isostere inhibitor Descriptor: (2S)-2-{[(2R,5S)-5-{[(2S,3S)-2-{[(2S,3R)-2-(acetylamino)-3-hydroxybutanoyl]amino}-3-methylpentanoyl]amino}-2-butyl-4-oxononanoyl]amino}-N~1~-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]pentanediamide, Chemical analogue HIV-1 protease Authors: Torbeev, V.Y, Mandal, K, Terechko, V.A, Kent, S.B.H. Deposit date: 2008-06-03 Release date: 2008-08-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site Bioorg.Med.Chem.Lett., 18, 2008
创建时间：
2008-06-03
