Adverse Outcome Pathway on Androgen receptor agonism leading to reproductive dysfunction (in repeat‑spawning fish)
收藏Organisation for Economic Co-operation and Development2026-04-11 收录
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https://www.oecd.org/en/publications/adverse-outcome-pathway-on-androgen-receptor-agonism-leading-to-reproductive-dysfunction-in-repeat-spawning-fish_b0c6838a-en.html
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This AOP details the linkage between binding and activation of androgen receptor (AR) in females and reductions in cumulative fecundity and spawning. AR-mediated activities are among the major concerns in endocrine disruptor screening programs. Cumulative fecundity is the apical endpoint considered in the OECD 229 Fish Short Term Reproduction...
