Allodynia quantification at day of cull (At least postoperative day 18).

Graded neuropathy was induced by varying the number of chromic gut pieces ligating the nerve (N) and/or distributed in the subcutaneous (S) compartments. The treatment groups were N0S0, N0S4, N1S0, N1S3, N2S0, N2S2 and N4S0 (n = 6/group). At baseline all rats responded very similarly and was not included in the statistical analysis. A significant group effect was observed at day of cull (PP = 0.03, N0S0 vs. N1S3; **P = 0.0002, N0S0 vs. N2S0, N0S0 vs. N2S2, N0S0 vs. N4S0; #P = 0.02, N0S4 vs. N2S0, N0S4 vs. N2S2, N0S4 vs. N4S4). Error bars on graphs represent standard error of the mean and significance is set at P