Copy number and expression profiling of multiple myeloma patients at multiple stages of their individual clinical course Identification of evolutionary patterns in multiple myeloma Gene expression an
By transplanting in competition multiple pre-leukemic clones in a cohort of primary recipients, we observed emergence of dominant clones during the development of AML. By sampling âwinnerâ clones
In large clonal populations, several clones generally compete which results in complex evolutionary and ecological dynamics: experiments show successive selective sweeps of favorable mutations as well
