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Proline-Catalyzed Diastereoselective Direct Aldol Reaction between 4-Oxoazetidine-2-carbaldehydes and Ketones

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Proline_Catalyzed_Diastereoselective_Direct_Aldol_Reaction_between_4_Oxoazetidine_2_carbaldehydes_and_Ketones/3074473
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资源简介:
The reaction of enantiopure 4-oxoazetidine-2-carbaldehydes with unmodified ketones was catalyzed by l-proline as well as by d-proline, to give the corresponding γ-amino-β-hydroxy ketones with good yields and diastereoselectivities. The obtained results implied that (2R,3R)-4-oxoazetidine-2-carbaldehydes and l-proline are a matched pair for diastereoselective induction.
创建时间:
2016-03-01
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