Genome-wide maps of FOXK2 binding sites in ovarian cancer cell line OVCAR5 and expression profile of FOXK2 knockdown OVCAR5 cells (RNA-seq)

This study characterized the genome-wide binding of FOXK2 in ovarian cancer (OC) cell OVCAR-5 and investigated the expression profile of OVCAR5 cells with FOXK2 knocking-down. Overall design: Two datasets are included: 1) Examined transcriptome of OVCAR5 cells transduced with control shRNA (shCtrl) and FOXK2-targeting shRNA (shFOXK2) in OVCAR5 cells (in biological duplicates); 2) Determined the genome-wide bindng and occupancy profile of FOXK2 in OVCAR5 cells by ChIP-seq (in biological duplicates).