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Borna disease virus, a negative-strand RNA virus, transcribes in the nucleus of infected cells.

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PubMed Central1992-12-01 更新2026-05-16 收录
下载链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC50576/
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资源简介:
Borna disease virus, an unclassified infectious agent, causes immune-mediated neurologic disease in a wide variety of animal hosts and may be involved in pathogenesis of selected neuropsychiatric diseases in man. Initial reports suggested that Borna disease virus is a single-stranded RNA virus. We describe here a method for isolation of viral particles that has allowed definitive identification of the genome as containing a negative-polarity RNA. Further, we show that the viral mRNAs are transcribed in the nucleus. IMAGES:
提供机构:
National Academy of Sciences
创建时间:
1992-12-01
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