Exon- expression data of Human hepatocellular carcinoma cells ( CD90 + HSP90 + HCC cells )

Identification of surface antigens that exhibited cancer-specific expression is a crucial step in the development of novel antibody-targeted therapies. We here aimed to investigate the anti-tumor activity of a novel monoclonal antibody (mAb) 11C9 and identify the antibody tractable target in the hepatocellular cancer stem cells (HCSCs). This research has studied differentially expressed genes (DEGs) between CD90+HSP90+ cells and 11C9-treated CD90+HSP90+ cells. We collected those two types cells for RNA extraction and hybridization on Affymetrix microarrays. 2 samples from CD90+HSP90+ cells, 1 sample treated by 11C9, 1 sample is normal CD90+HSP90+ cells.