Mechanistic Model-Guided Study of Embryonic Morphogenesis
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
下载链接：
http://data.iscr.ac.cn/Article?id=7eef8305e0d333e1d090eb5b64ba6ae1
下载链接
链接失效反馈官方服务：
资源简介：
We utilize a finite element model of implantation mechanics to guide the in vitro micropatterning human embryonic stem cells to simulate in vivo stress gradients that form during development. Micropatterned stem cells showed early formation of GATA4+/SOX17+ primitive endoderm due to migration toward regions of high stress, while NANOG+/OCT4+ epiblast was retained in regions of low stress under spontaneous differentiation.
提供机构：
The Hebrew University of Jerusalem
创建时间：
2022-02-20
