LPS-induced TNFα responsive module genes linked to transcriptional initiation, elongation and epigenetic regulation.

Genes within LPS-induced TNFα responsive co-expression modules possessing epigenetic regulation, transcriptional initiation and elongation properties. kTotal, total connectivity, k. kWithin, intra-modular connectivity. kOut, extra-modular connectivity. log2 FC LPS, log2 transformed foldchange for the placebo-treated pre- and post-LPS challenged samples. log2 FC LPS+Etan, log2 transformed foldchange for the etanercept-treated pre- and post-LPS challenged samples. Gene names marked in bold type denote module genes identified as top module hub genes.