Gram-Scale Synthesis of 3‑Sulfonyl Flavanones
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https://figshare.com/articles/dataset/Gram-Scale_Synthesis_of_3_Sulfonyl_Flavanones/11398095
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资源简介：
In this paper, an easy-operational, high-yielding method
for the
gram-scale synthesis of 3-sulfonyl flavanones is described by a one-pot
straightforward POCl3 mediated intermolecular (5 + 1) annulation
of the β-ketosulfones with an o-hydroxyaryl
group (dual nucleophile) and arylaldehydes (dual electrophile) in
refluxing toluene for 3 h. A plausible mechanism is proposed and discussed.
This protocol provides a highly effective annulation via one carbon–oxygen
(C–O) and one carbon–carbon (C–C) bond formations.
创建时间：
2019-12-05
