five

Parameters of the final regression model.

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%SEE = percent standard error of parameter estimate, *95% confidence interval of the parameter obtained as the 2.5th and 97.5th percentiles of the results of 1000 model runs using Bootstrap resampling with NONMEM. AU: Arbitrary unit used for the above-mentioned numerical re-definition of the cues. #: Not estimated because the parameter was not part of the final model as it had not provided a significant improvement of fit during the model building (fitting) process. Specifically, the percentages of stimuli at pain threshold level rated as painful were associated with the three different cues using a linear model of PercentRatedAsPain=Slope⋅ θ1 2−Group ⋅θ2 Sex ⋅Cue+Y_Intersection⋅θ3 2−Group ⋅θ4 Sex , where Cue = [–1,0,1] for “no pain”, “stimulus or neutral cue, and “pain”, respectively; Group = [1,2]; and Sex = [0,1] for women and men, respectively. The fits are plotted in Fig 2. The final model was the result of goodness-of-fit statistics. Only parameters that provided a statistically significant improvement when free to be estimated remained part of the final model, which therefore, in its short form reads as PercentRatedAsPain=39.5 % AU ⋅( − 0.526 2−Group ) ⋅Cue+24.1% .
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2015-07-06
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