Supplementary Material for: COVID-19 in patients with active - higher inflammatory activity predicts poor outcome.

Abstract
Introduction: Active malignancies have been identified as an independent risk-factor for severity and mortality in COVID-19. However, direct comparisons between SARS-CoV-2 infected patients with active (acP) and non-active cancers (n-acP) remain scarce.
Patients and Methods: We retrospectively analyzed a cohort of cancer patients with PCR confirmed SARS-CoV-2 infection, enrolled from 03/16/2020 to 07/31/2021. Data on demographics, cancer, and laboratory findings were collected. Descriptive and subsequent regression analysis was performed. Endpoints were “deterioration to severe COVID-19” and “infection-associated mortality”.
Results: In total, 987 cancer patients (510 acP vs 477 n-acP) were included in our analysis. The majority was >55 years, more men than women were included. At detection of SARS-CoV-2, 65.5% of patients had mild/moderate symptoms, while deterioration to severe COVID-19 was slightly more common in acP (19% vs 16%; p=0.284). COVID-19-associated mortality was significantly higher in acP (24% vs 17.5%, p

摘要
引言：活跃的恶性肿瘤已被确认为新冠肺炎严重程度和死亡率的一个独立风险因素。然而，关于SARS-CoV-2感染患者中活跃癌症（acP）与无活跃癌症（n-acP）之间的直接比较仍然相对罕见。
患者与方法：我们对一组通过PCR确诊为SARS-CoV-2感染且患有癌症的患者进行了回顾性分析，这些患者于2020年3月16日至2021年7月31日期间入组。收集了关于人口统计学、癌症和实验室检查结果的数据。进行了描述性分析和后续回归分析。终点指标为“病情恶化至重症新冠肺炎”和“感染相关死亡率”。
结果：在我们的分析中，共纳入987名癌症患者（510例acP与477例n-acP）。其中大多数患者年龄大于55岁，男性患者多于女性。在检测到SARS-CoV-2时，65.5%的患者表现出轻度/中度症状，而在acP患者中，病情恶化至重症新冠肺炎的发生率略高（19% vs 16%；p=0.284）。与COVID-19相关的死亡率在acP患者中显著升高（24% vs 17.5%，p