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Human unphosphorylated IGF1-R Kinase domain in complex with an hydantoin inhibitor

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3o23
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Human unphosphorylated IGF1-R Kinase domain in complex with an hydantoin inhibitor Descriptor: (5S)-5-methyl-1-(quinolin-4-ylmethyl)-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione, Insulin-like growth factor 1 receptor Authors: Maignan, S, Guilloteau, J.P, Dupuy, A. Deposit date: 2010-07-22 Release date: 2011-05-04 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: Advantages in comparison with competitive inhibitors Bioorg.Med.Chem.Lett., 21, 2011
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2010-07-22
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