Recruitment of Profilin by Ena/VASP proteins
收藏reactome.org2025-01-09 收录
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Ena/VASP proteins (ENAH, EVL1 and VASP) enhance actin filament elongation via the recruitment of profilin:actin complexes to the tips of spreading lamellipodia. Profilin (PFN1 or PFN2) binds to the central proline rich domain of an Ena/VASP protein (Bashaw et al. 2000).
Ena/VASP蛋白(ENAH、EVL1和VASP)通过募集profilin:actin复合物至扩展伪足尖端,增强肌动蛋白丝的延长。profilin(PFN1或PFN2)与Ena/VASP蛋白(Bashaw等,2000年)的中心脯氨酸富集区域结合。
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