A whole-genome sequencing dataset of nanopore raw signals for bacterial genotyping and methylation analysis - further information on AMR and BioProject
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Additional Material for the publication "A whole-genome sequencing dataset of nanopore raw signals for bacterial genotyping and methylation analysis" Bioproject Information: List of all BioSamples in BioProject PRNJA1091452 with the relevant metadata to the origin of the isolates and novel SRA accession numbers for all experiments containing raw squiggle data. All other SRA accession numbers from the BioProject pertain to previous publications. Phenotypic AMR testing: Phenotypic antimicrobial resistance testing results for three different species Enterococcus faecium (EF), Klebsiella pneumoniae (KP) and Staphylococcus aureus (SA). The tested antibiotics for each bacterial species were selected and interpreted based on the EUCAST 2023 guidelines. The interpretation is based on the minimum inhibitory concentration (MIC) values and is categorized as R (resistant), S (susceptible), or I/*R (intermediate), according to species- and antibiotic-specific breakpoints. A ‘+’ before an antibiotic name indicates combined resistance with the previous antibiotic. For several antibiotics tested in KP the MIC values and interpretations differ depending on the use case and therefore present several possible test results for one antibiotic.



