Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures.. Mus musculus

Transcriptome profile of whole tissue and cultured neuronal cells from the hippocampus and cortex from pooled littermate embryos (at 17-18 days post conception) of 2 mouse genotypes C57BL/6 congenic WT and Fmr1 KO. Overall design: Fragile X mouse model, whole tissue and cultured neuronal cells from the hippocampus and cortex Pooled whole tissue or cultured cells from the central nervous system of embryonic mouse littermates of 2 genotypes.