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表达IFNα的间充质基质细胞赋予T细胞强大的抗肿瘤免疫力
免疫检查点阻断疗法的出现已经彻底改变了癌症治疗方法。然而，只有少数不同类型的肿瘤患者从这些治疗中获益。针对肿瘤组织微环境中免疫情况的新策略具有巨大的前景。在此，我们创造了过表达IFNα的间充质基质细胞（IFNα-MSCs）。在直接注射到肿瘤中后，我们发现这些细胞可以有效地消除多种类型的肿瘤。有趣的是，IFNα-MSCs的肿瘤内注射也可以在远处的肿瘤中产生特异性的抗肿瘤作用。这些IFNα-MSCs促
干细胞与再生医学数据中心2023-05-03 更新130
Circular RNAs show differential expression profiles and may be potential therapeutic targets by acting as ceRNAs in cholesteatoma
In our present study, we explored the circRNA expression profiles in cholesteatoma by deep RNA-seq analysis. We obtained totally 355 significantly differentially expressed circRNA in cholesteatoma, am
NIAID Data Ecosystem60
Additional file 1 of Comprehensive landscape and future perspectives of circular RNAs in colorectal cancer
Additional file 1. Expression profiling of circRNAs in colorectal cancer [212–223].
Figshare2024-02-08 更新60
Additional file 8 of Characterization of distinct circular RNA signatures in solid tumors
Additional file 8: Table S11. The expression profiles of 439 tissue-specific circRNAs.
Figshare2024-02-23 更新90
Additional file 6: of Detection of circular RNA expression and related quantitative trait loci in the human dorsolateral prefrontal cortex
Table S5. List of circRNAs associated with age of death at an FDRâ<â0.05. (XLSX 30 kb)
NIAID Data Ecosystem60
