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E. coli Dihydropteroate Synthase in complex with pterin-based inhibitor

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Protein Data Bank Japan2025-11-26 更新2026-04-19 收录
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E. coli Dihydropteroate Synthase in complex with pterin-based inhibitor Descriptor: 7-amino-1-methyl-3-{[(1H-tetrazol-5-yl)amino]methyl}pyrimido[4,5-c]pyridazine-4,5(1H,6H)-dione, Dihydropteroate synthase Authors: Snoke, H.E, Reeve, S.M, Lee, R.E. Deposit date: 2025-06-18 Release date: 2025-11-05 Last modified: 2025-11-26 Method: X-RAY DIFFRACTION (2.141 Å) Cite: Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria. Acs Infect Dis., 11, 2025
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2025-06-18
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