JAK1 kinase (JH1 domain) in complex with compound 72
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https://pdbj.org/mine/summary/4fk6
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JAK1 kinase (JH1 domain) in complex with compound 72 Descriptor: N-({1-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl}methyl)methanesulfonamide, Tyrosine-protein kinase JAK1 Authors: Eigenbrot, C, Steffek, M. Deposit date: 2012-06-12 Release date: 2012-11-07 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2. Bioorg.Med.Chem.Lett., 22, 2012
创建时间：
2012-06-12
