Medial prefrontal cortex (mPFC) transcriptome analysis of Shank3-overexpressing mice
收藏NIAID Data Ecosystem2026-05-26 收录
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资源简介：
Shank3 is a core excitatory postsynaptic protein expressed in multiple brain regions including the medial prefrontal cortex, striatum, and hippocampus. We have previously generated and characterized Shank3-overexpressing transgenic mice, and found that these mice exhibited manic-like behavioral phenotypes. To understand molecular mechanisms underlying the behavioral changes, we performed transcriptome (RNA-sequencing) analysis of the mPFC tissues from 10 to 12-week-old wild-type and Shank3 transgenic mice. Overall design: Medial prefrontal cortex (mPFC) transcriptome of 10 to 12-week-old wild-type and Shank3 transgenic (TG) mice.
创建时间：
2019-02-23
