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Global hepatic gene expression data from PPARa liver-specific KO and PPARa liver wild-type male mice fed ad libitum. Mus musculus

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NIAID Data Ecosystem2026-03-10 收录
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To identify genes whose expression is under the strict dependence of hepatocyte PPARa activity, we used a mouse strain of PPARa-specific deletion in hepatocyte (albumin-Cre+/- Pparaflox/flox or LKO) and we compared them to their liver WT littermates (albumin-Cre-/- Pparaflox/flox or LWT) fed ad libitum or fasted for 24 hours. Overall design: There are 24 liver samples, each from an individual mouse. The samples are from Ppara liver KO (LKO) and liver WT (LWT) male mice of 8 week-old from the same genetic background (C57Bl/6J) fed ad libitum or fasted for 24 hours (n=6 mice/genotype/group). All mice were sacrified at ZT16.

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2017-03-13
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