Crystal structure of human TLR8 in complex with compound 34
收藏Protein Data Bank Japan2024-10-16 更新2026-04-19 收录
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Crystal structure of human TLR8 in complex with compound 34 Descriptor: (3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)-3-methyl-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-1-yl]methyl]-1-bicyclo[2.2.2]octanyl]morpholine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... Authors: Faller, M, Zink, F. Deposit date: 2023-06-16 Release date: 2023-08-16 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.785 Å) Cite: Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune Diseases. Acs Med.Chem.Lett., 14, 2023
创建时间：
2023-06-16
