IRAK4 in complex with compound 23
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IRAK4 in complex with compound 23 Descriptor: Interleukin-1 receptor-associated kinase 4, N-{1-[(1R,2S)-2-fluorocyclopropyl]-2-oxo-1,2-dihydropyridin-3-yl}-2-[(1R,4r)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-6-[(propan-2-yl)oxy]-2H-pyrazolo[3,4-b]pyridine-5-carboxamide Authors: Metrick, C.M, Chodaparambil, J.V. Deposit date: 2023-08-18 Release date: 2024-06-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors. Acs Med.Chem.Lett., 15, 2024
创建时间：
2023-08-18
