Additional file 1 of Cardiac magnetic resonance markers of pre-clinical hypertrophic and dilated cardiomyopathy in genetic variant carriers

Additional file 1: Tables S1–S14. Table S1 Genes with pathogenic and likely pathogenic variants for hypertrophic cardiomyopathy or dilated cardiomyopathy. Table S2 Disease definitions based on ICD-10 codes and self-reported codes. Table S3 Baseline table for participants of the UK Biobank without established cardiac diseaseat the time of cardiac imaging visit. Table S4 Hazard ratio estimates for the association between CMR measurementsand the onset of atrial fibrillation and heart failure in people without established cardiac disease at the time of their imaging visit. Table S5 Hazard ratio estimates for the association between binary CMR measurementsand the onset of atrial fibrillation and heart failure in people without established cardiac disease at the time of their imaging visit. Table S6 Odds ratio estimates for the association between CMR measurementsand carriership of a HCM variant in people without established cardiac disease at the time of imaging visit. Table S7 Odds ratio estimates for the association between CMR measurementsand carriership of a DCM variant in people without established cardiac disease at the time of imaging visit. Table S8 Baseline characteristics before and after imputation. Table S9 Exploring potential non-linear associations between CMR measurements and carriership of cardiomyopathy-associated variants using a multivariable model. Table S10 Sex-specific subgroup analyses for the association between CMR measurements and carriership of cardiomyopathy variants. Table S11 Age-specific subgroup analyses for the association between CMR measurements and carriership of cardiomyopathy variants. Table S12 Heterogeneity of the observed associations between CMR measurements and the three most common HCM and DCM genes. Table S13 Odds ratio estimates for the association between CMR measurements and the three most common HCM and DCM-associated genes. Table S14 Common genetic variants in or around known cardiomyopathy genes associated with CMR measurements in GWAS.