ISTransbase

ISTransbase is a comprehensive database that consolidates data on 16,528 inhibitors and 4,465 substrates of 163 drug transporters from 18 species, providing detailed insights into transporter structures, functions, and interactions. It serves as a valuable resource for researchers and clinicians exploring drug transporter mechanisms and mitigating adverse drug reactions.

搜集汇总

背景与挑战

背景概述

ISTransbase是一个专注于药物转运体抑制剂和底物的综合数据库，包含超过90,000条抑制剂条目和50,000条底物条目，涵盖163个转运体。它提供多维实验信息和高效搜索工具，旨在支持药物研发和临床应用，更新于2023年6月。