Expression data of health individuals and newly diagnosed multiple myeloma. Expression data of health individuals and newly diagnosed multiple myeloma

Multiple myeloma is a multi-stage disease. Based on its laboratory and clinical presentation it can be summarized as MGUS, smoldering myeloma, and multiple myeloma. Previous studies have shown that the expression levels of miRNAs in different stages of the disease are different. This study analyzes the expression levels of miRNAs in healthy individuals and myeloma serum exosomes. We used microarrays to detail the miRNAs expressionin between 12 healthy individuals and 12 multiple myeloma and identified distinct classes of dys-regulated genes. Overall design: Collecting multiple myeloma patients and healthy individuals peripheral blood and serum and extract exosomes, extract exosome RNA, and hybridize on Affymetrix microarrays.