Analyzing the importance of Arabidopsis AtLBR-2 in lipopolysaccharide (LPS)-induced defense responses by RNA-Seq

Lipopolysaccharide (LPS) from Gram-negative bacteria cause innate immune responses in animals and plants. LPS signaling mechanisms of animals has been well studied, while that of plants is still almost unknown. Recently, we have identified Arabidopsis AtLBR-2 which binds to LPS directly and regulates LPS-induced defense responses. In this project, we investigated the LPS-induced transcriptomic changes in wild-type (WT) and atlbr-2 mutant Arabidopsis using RNA-Seq technology. Comparative analysis of differentially expressed genes between WT and atlbr-2 mutant identified the importance of AtLBR-2 in LPS-induced defense responses.