This dataset contains the drugscreen of the known bioactives library (Enzo Screen Well BML 2840) including the imaging data (time lapse bright-field microscopy of zebrafish embryos until 26hpf) and th
*: The frequency of drugs appeared in top 20 drugs in group 1 and group 2. **: Effectiveness in the clonogenic assay is defined as reducing the number of colonies by more than 50% at 10 µM. Table is s
Full details of the SelleckChem FDA-approved drug library used for the screening assay as outlined in our manuscript. Dataset includes the names of the 1,954 drugs along with the following information
Sirt1/2 inhibition activity was measured as described in “Materials and Methods”. Data are presented as mean ± SD (n = 6). The data in the parentheses are Sirt1 inhibition.
