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Systematic analysis of differential rhythmic kidney gene expression

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Many reports support a link between circadian rhythm and renal diseases. However, these dysregulated clock-controlled genes in kidney have mainly focused on the protein-coding genes. Here, we try to identify these circadian long-coding RNA (lncRNAs) in renal tissue. To obtain the rhythmic gene expression in mouse kidney, we performed RNA sequencing (RNA-seq) with RNA from mouse kidneys collected every 4 h respectively under light/dark (LD) cycle.

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