Synthesis of Trifluoromethylated Naphthoquinones via Copper-Catalyzed Cascade Trifluoromethylation/Cyclization of 2‑(3-Arylpropioloyl)benzaldehydes
收藏Figshare2017-03-06 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Synthesis_of_Trifluoromethylated_Naphthoquinones_via_Copper-Catalyzed_Cascade_Trifluoromethylation_Cyclization_of_2_3-Arylpropioloyl_benzaldehydes/4726228
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A novel copper-catalyzed cascade trifluoromethylation/cyclization of 2-(3-arylpropioloyl)benzaldehydes is described, allowing a direct access to structurally diverse trifluoromethylated naphthoquinones under mild reaction conditions. It represents the first trans-acyltrifluoromethylation of internal alkynes.
创建时间:
2017-03-06



