B-Raf V600E Kinase Domain Bound to a Type II Dihydroquinazoline Inhibitor
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B-Raf V600E Kinase Domain Bound to a Type II Dihydroquinazoline Inhibitor Descriptor: 3-(2-cyanopropan-2-yl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide, Serine/threonine-protein kinase B-raf Authors: Voegtli, W.C, Sturgis, H.L. Deposit date: 2012-07-24 Release date: 2012-11-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Pyrazolopyridine inhibitors of B-Raf(V600E). Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
创建时间：
2012-07-24
