Friedel−Crafts-Type Cyclization of 2,2-Difluorovinyl Ketones via α-Fluorocarbocations and Its Application in Domino Cyclizations
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https://figshare.com/articles/dataset/Friedel_Crafts_Type_Cyclization_of_2_2_Difluorovinyl_Ketones_via_Fluorocarbocations_and_Its_Application_in_Domino_Cyclizations/3069799
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资源简介：
2,2-Difluorovinyl ketones bearing an aryl group undergo Friedel−Crafts-type cyclization via carbocations stabilized by α-fluorines on treatment
with a trimethylsilylating agent [Me3SiOTf or Me3SiB(OTf)4]. The reaction affords 4-fluorinated 3-acyl-1,2-dihydronaphthalenes, which are
successfully subjected to a substitution−cyclodehydration process or a Nazarov-type cyclization to construct fused polycyclic systems.
创建时间：
2016-03-01
