Crystal structure of human FTO in complex with acylhydrazine inhibitor 16
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Crystal structure of human FTO in complex with acylhydrazine inhibitor 16 Descriptor: (2E)-4-{N'-[4-(4-tert-Butyl-benzyl)-pyridine-3-carbonyl]-hydrazino}-4-oxo-but-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION Authors: Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G. Deposit date: 2014-04-09 Release date: 2014-10-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.76 Å) Cite: A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO. Chem Sci, 6, 2015
创建时间：
2014-04-09
