Pathway enrichment analysis for deregulated miRNAs in mouse primary hippocampal neurons after Aβ treatment.

*The total number of target genes predicted to be regulated by individual miRNAs was calculated using TargetScanMouse v5.1. Note that TargetScan gives lists of predicted targets for miRNA families and not for individual family members due to sequence similarity. **Gene lists were uploaded into DAVID bioinformatic database and the number of targets recognized by DAVID assigned to known KEGG pathways is given. ***Enrichment analysis showing KEGG Pathways likely to be affected by predicted targets of deregulated miRNAs are indicated using a cut-off P-value of 0.01. The most significant pathways with a P-value of 0.001 are shown in bold. ****For each pathway predicted to be affected the number of miRNA target genes in that pathway is indicated followed by the total number of genes in that pathway in brackets.