Iridium Catalyzed Asymmetric Hydrogenation of Cyclic Imines of Benzodiazepinones and Benzodiazepines
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https://figshare.com/articles/dataset/Iridium_Catalyzed_Asymmetric_Hydrogenation_of_Cyclic_Imines_of_Benzodiazepinones_and_Benzodiazepines/2499652
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Highly enantioselective Ir-catalyzed hydrogenation of seven-membered cyclic imines of benzodiazepinones and benzodiazepines was achieved with up to 96% ee. This method provides a direct access to synthesize a range of chiral cyclic amines existing in numerous important natural products and clinical drugs.
创建时间：
2016-02-20
