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Isolation and Structure Elucidation of Pentahydroxyscirpene, a Trichothecene Fusarium Mycotoxin

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Figshare2015-12-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Isolation_and_Structure_Elucidation_of_Pentahydroxyscirpene_a_Trichothecene_i_Fusarium_i_Mycotoxin/2039127
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Pentahydroxyscirpene, a novel trichothecene-type compound, was isolated from Fusarium-inoculated rice. The structure of pentahydroxyscirpene was elucidated by 1D and 2D NMR spectroscopy and X-ray single-crystal diffraction. The conformation in solution was determined by NOESY experiments supported by quantum chemical calculations. In vitro toxicity tests showed that pentahydroxyscirpene inhibits protein synthesis as do other trichothecenes.
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2015-12-17
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