IL-18 Inhibition Aggravates Atherosclerosis in Jak2V617F Clonal Hematopoiesis
收藏官方服务：
资源简介：
IL-18 Inhibition Aggravates Atherosclerosis in Jak2V617F Clonal Hematopoiesis
应用场景：
创建时间：
2025-10-30
相关数据集
Data_Sheet_1_Stimulation of the PD-1 Pathway Decreases Atherosclerotic Lesion Development in Ldlr Deficient Mice.PDF
Aim: Signaling through the coinhibitory programmed death (PD)-1/PD-L1 pathway regulates T cell responses and can inhibit ongoing immune responses. Inflammation is a key process in the development of a
NIAID Data Ecosystem90
The cathelicidin protein CRAMP is a potential atherosclerosis self-antigen in ApoE(-/-) mice
Auto-immunity is believed to contribute to inflammation in atherosclerosis. The antimicrobial peptide LL-37, a fragment of the cathelicidin protein precursor hCAP18, was previously identified as an au
NIAID Data Ecosystem60
The T cell-DC CD40L-CD40 axis, but not platelet CD40L, drives atherosclerosis
Atherosclerosis, the underlying vascular cause of cardiovascular disease, has a strong inflammatory component. The co-stimulatory CD40-CD40 ligand (CD40L) signaling axis is a pivotal regulator of immu
NIAID Data Ecosystem40
Cross-Reacting Antibacterial Auto-Antibodies Are Produced within Coronary Atherosclerotic Plaques of Acute Coronary Syndrome Patients
Coronary atherosclerosis, the main condition predisposing to acute myocardial infarction, has an inflammatory component caused by stimuli that are yet unknown. We molecularly investigated the nature o
NIAID Data Ecosystem80
Decoding the immune checkpoint signatures in human atherosclerosis: implications of type 2 diabetes and lipid-lowering intervention [human_carotid_plaque]
Immune checkpoint inhibitor (ICI) therapies in cancer accelerate atherosclerosis progression. Here, we have charted the landscape of immune checkpoint gene expression and defined the network of diseas
NIAID Data Ecosystem40
