ʻInhibitoryʼ Test Paradigms: Demographics and Drugs.

§ not interfering with the MOR-antagonist assessments (drugs without administration route stated are i.v.).¤ 3 additional volunteers were included due to unintended ʻcarry-overʼ (sequence) effects.# 12 volunteers total (2 volunteers did not participate in the naloxone parts of the study).SD standard deviation.A = age presented separately for each of the 6 groups of volunteersB = bolus (up to 4 min administration time allowed); F = female; I = infusion; M = male; ITP = iontophoresis; N.R. = not reported; NTx = naltrexone; Nx = naloxone; SD = standard deviation; TCI = target-controlled infusion (total dose indicated).ʻInhibitoryʼ Test Paradigms: Demographics and Drugs.