Crystal structure of ROCK2 in complex with a 8-(azaindolyl)-benzoazepinone inhibitor

Crystal structure of ROCK2 in complex with a 8-(azaindolyl)-benzoazepinone inhibitor Descriptor: 1,2-ETHANEDIOL, 8-(azaindolyl)-benzoazepinone, Rho-associated protein kinase 2 Authors: Pala, D, Clark, D, Pioselli, B, Accetta, A, Rancati, F. Deposit date: 2024-03-18 Release date: 2024-09-25 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.63 Å) Cite: Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors. Rsc Med Chem, 15, 2024