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The role of Raf-1 kinase inhibitor protein in the regulation of pancreatic beta cell proliferation in mice

ChEBI2012-11-19 更新2026-07-21 收录

β细胞增殖

Raf-1激酶抑制蛋白功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31150 数据链接链接失效反馈

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The role of Raf-1 kinase inhibitor protein in the regulation of pancreatic beta cell proliferation in mice

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创建时间：

2012-11-19

β细胞增殖

单细胞转录组学

The functional mass of insulin-secreting pancreatic β cells expands to maintain glucose homeostasis in the face of nutrient excess, in part via replication of existing β cells. To decipher the underly

NIAID Data Ecosystem140

Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B.

β细胞增殖

肥胖诱导2型糖尿病

Comparison of gene expression in pancreatic islets of BTBR-ob/ob mouse model of obesity-induced type 2 diabetes, and in non-diabetic control mice, B6-ob/ob identified Asf1b as an important gene candid

NIAID Data Ecosystem70

RNA sequencing discerns sub-populations of pancreatic Ã-cells and dynamics of gene expression in partial pancreatectomy model

单细胞转录组学

β细胞增殖

We employed single-cell RNA sequencing of islets in young mice subjected to partial pancreatectomy (PPTx). Four clusters of pancreatic beta cells including a subpopulation of replicating beta cells. P

NIAID Data Ecosystem20

Cell Cycle–Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

胰腺发育生物学

β细胞增殖

Organogenesis relies on the spatiotemporal balancing of differentiation and proliferation driven by an expanding pool of progenitor cells. In the mouse pancreas, lineage tracing at the population leve

NIAID Data Ecosystem80

Mus musculus Raw sequence reads. Mus musculus

β细胞增殖

转录组学分析

We have constructed a model to induce the proliferation of pancreatic beta cells by a short-term high-fat diet and attempted to explore the underlying mechanism by transcriptomics.

NIAID Data Ecosystem30

The role of Raf-1 kinase inhibitor protein in the regulation of pancreatic beta cell proliferation in mice

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