The SCFA-producing commensal bacteria protect from enteric viruses via cGAS-STING-type I IFN axis

The microbiota-associated factors that influence host susceptibility and immunity to enteric viral infections remain poorly defined. We launched the current study to identify the specific commensal bacteria species and illustrate the mechanisms of how they regulate the host mucosal and systemic antiviral innate immunity against enteric virus infections using mouse model.