Supplementary Table 6 from Expression Levels of Therapeutic Targets as Indicators of Sensitivity to Targeted Therapeutics

Supplementary Table 6a: Spearman correlation values between drug sensitivity and target expression for 86 drugs common between GDSC and CTRP. Supplementary Table 6b: Correlation matrix comparing gene expression values. There are 558 cell lines and 15,934 genes common between both the datasets. Calculated 558x 558 - Correlation matrix comparing gene expression values for 15,934 genes in one cell line from GDSC compared to 15,934 genes in CTRP. Correlation method used was Spearman. Supplementary Table 6c: Spearman correlation values comparing Area under the curve (AUC) values across common cell lines in the GDSC and CTRP datasets for the 86 drugs common between them. Supplementary Table 6d: List of the cell lines where a better gene expression correlation was observed with a different cell line.

补充表6a：GDSC与CTRP之间86种药物的药物敏感性与其靶基因表达之间的Spearman相关系数。补充表6b：基因表达值的相关性矩阵。两个数据集中共有558个细胞系和15,934个基因。计算558x558的相关矩阵，比较单个细胞系中GDSC的15,934个基因与CTRP的15,934个基因的基因表达值相关性。所使用的相关性方法为Spearman。补充表6c：比较GDSC与CTRP数据集中共同细胞系86种药物的曲线下面积（AUC）值的Spearman相关系数。补充表6d：列出在观察到的基因表达相关性中与不同细胞系有较好关联的细胞系列表。