Deciphering functions of VHL in Clear Cell Renal Cell Carcinoma
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https://www.omicsdi.org/dataset/pride/PXD012665
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VHL is the most frequently mutated gene in ccRCC.It functions via the oxygen-dependent ubiquitin-mediated degradation of hypoxia-inducible factor (HIF). The stabilization and hyperactivation of HIF1 play essential roles in tumorigenesis. This is a TMT based proteomics experiment aimed to investigate the functions of VHL in ccRCC systematically.
创建时间:
2023-01-05



