SID-SRM-MS measurements of candidate biomarkers in IPA.

A). SID-SRM-MS measurements of the discovery cohort. For each candidate biomarker, the SID-SRM-MS measurements by disease category are shown. Box plots show the 25% and 75% interquartile range and the median value, indicated by horizontal dark line. Outliers are signified with circles. Note that the median horizontal line is not symmetrically located within the box plot, signaling that the data are not normally distributed. P values are from Wilcoxon ranked sum. B). SID-SRM-MS of the validation cohort. Data are presented as in Panel A.