Gene expression analysis of chicken dendritic cells (DCs) in response to H9N2 avian influenza virus infection

We analyze the differentially expressed genes (DEGs) at the transcriptome level in chicken DCs infected with H9N2 influenza virus compared to mock infection by high-throughput RNA-sequencing technology, and found that H9N2 influenza virus infection induced a strong innate immune response in chicken DCs, but impaired the antigen-processing and –presenting capacity of this cell, Gene expression profiles of chicken DCs infected without or with H9N2 influenza virus were generated by deep sequencing, in triplicate, using Illumina HiSeq X