Cross-ancestry and sex-stratified genome-wide association analyses of amygdala and subnucleus volumes.

Multivariate GWASs for 21 amygdala volumetric traits were conducted using CGWAS, separately in the CHIMGEN and UKB datasets, and in cross-ancestry analyses with sex-combined data. A EUR-GWAS meta-analysis for the mean volume of the bilateral amygdala was conducted based on GWAS summary statistics (n = 48,634; including UKB and ENIGMA), and a cross-ancestry analysis for the same trait was performed with a total sample size of 55,557 (including UKB, ENIGMA and CHIMGEN).