Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, encoding for a chloride ion channel. Membrane expression of CFTR is negatively regul
Additional file 1: Table S1. Minor allele frequencies (MAF) of the 361 genotyped CFTR variants in a Mexican population. The table shows dbSNP ID, DNA HGVS ID, PROTEIN HGVS ID, Variant type, Clinical s
Analysis of the cystic fibrosis gene Cftr in the colon and small intestine of Cftr-deficient murine model. The hypothesis was loss of Cftr altered expression of genes important in intestinal homeostas
Identification of in vitro PKA phosphorylation sites in human titin fragment (amino acids 9689-9988, NCBI:NP_001254479.2) fused to TEV cleavage site and HALOtag (amino acids 3-296, NCBI:AQS79242.1) .
Secretory diarrhea, a major global health concern, particularly among young children, is often characterized by excessive chloride secretion through the cystic fibrosis transmembrane conductance regul