Secretory diarrhea, a major global health concern, particularly among young children, is often characterized by excessive chloride secretion through the cystic fibrosis transmembrane conductance regul

NIAID Data Ecosystem30

CF (1567) vs CFTR-corrected (1566) iPSC-airway at ALI. CF (1567) vs CFTR-corrected (1566) iPSC-airway at ALI

囊性纤维化

CFTR药物研究

To interrogate the intrinsic effect of CFTR on airway epithelium; to interrogate the presence of FOXi1+ASLC3+ ionocyte population. Description of samples:1567 (F508del CF patient of rapid progressive

NIAID Data Ecosystem20

Unique presentations and chronic complications in adult cystic fibrosis: do they teach us anything about CFTR?

囊性纤维化临床

CFTR药物研究

The increase in numbers of adults with cystic fibrosis (CF) has allowed us to identify previously unrecognized chronic complications of CF, as well as appreciate...

data.gov60

Mapping of p140Cap Phosphorylation Sites: The EPLYA and EGLYA Motifs Have a Key Role in Tyrosine Phosphorylation and Csk Binding, and Are Substrates of the Abl Kinase

蛋白质磷酸化位点鉴定

激酶底物功能研究

Protein phosphorylation tightly regulates specific binding of effector proteins that control many diverse biological functions of cells (e. g. signaling, migration and proliferation). p140Cap is an ad

NIAID Data Ecosystem20

Phospho-sites identified in mouse CFTR expressed in yeast.

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